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Figure 5 | BMC Structural Biology

Figure 5

From: Binary classification of protein molecules into intrinsically disordered and ordered segments

Figure 5

Frequencies of various modifications occurring in ID regions. The protein modifications considered are: alternative splicing (AS) boundary, phosphorylation (Phos), breakpoint in chromosomal translocation (Break), N-linked and O-linked glycosylation (N-link, O- link), cleavage by protease (Cleav), and disulfide bond (SS). The subcellular localizations are abbreviated as in Figure 4. The bar of phosphorylation in nucleus, for instance, indicates the fraction of phosphorylation sites occurring in ID regions in nuclear proteins. If phosphorylation sites were evenly distributed throughout SDs and ID regions in nuclear proteins, the fraction would be the same as the corresponding fraction of ID regions. The internal standards are presented as navy blue bars.

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